Mathematical model for predicting the effectiveness of pulmonary tuberculosis treatment based on the HOMA index and the atherogenicity index

Abstract

Carbohydrate metabolism disorders increase the risk of developing active tuberculosis and are associated with worse outcomes of tuberculosis treatment. 15% of tuberculosis cases worldwide are estimated to be related to diabetes mellitus. Altered lipid metabolism may influence susceptibility to tuberculosis. Studies have been published on the association between total cholesterol, low-density lipoprotein, and high-density lipoprotein levels and the risk of tuberculosis. Patients with tuberculosis have an increased incidence of cardiovascular and cerebrovascular diseases. Cardiovascular complications of tuberculosis are among the most common extrapulmonary manifestations of the disease.